![]() The progression of symptoms was notably slow, there was a significant family history and unlike typical PD, there were fewer nonmotor features. Although this constellation of features was tempting to be categorized as PD, the clinicians at Mayo Clinic observed unique differences. These patients had a pronounced asymmetric resting tremor in conjunction with mild to moderate postural and action tremor and mild parkinsonian signs. Benign tremulous parkinsonism was first characterized extensively in cohort of 16 patients followed at Mayo Clinic who shared similar phenotype and exhibited a unique clinical course. The basic difference between the arm tremors seen in these two conditions is that essential tremor is characterized by postural and action tremor whereas PD tremor is mostly a resting tremor. The most common cause of tremors is essential tremor and the other important differential is idiopathic Parkinson’s disease (PD). ![]() ![]() Tremor is a common symptom seen in movement disorders clinical practice. ![]()
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